Pathophysiology of Myelodysplastic Syndromes

Ineffective hematopoiesis is the major characteristic of early myelodysplastic syndromes.Its pathophysiology relies on a diversity of mechanisms supported by genetic events that develop in aging hematopoietic stem cells.Deletion and mutations trigger epigenetic modifications, and co-transcriptional and post-transcriptional deregulations of gene exp

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Robust learning-based fault prediction method for gyrotron system

During the high-power long-pulse operation of the gyrotron, radio frequency (RF) oscillation faults may occur, which can affect the stable operation of the electron cyclotron resonance heating system.Recently, some research has begun to use deep learning to diagnose RF oscillation faults in the gyrotron.However, these learning-based methods have ov

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Effect of Schistosoma haematobium infection on the cognitive functions of preschool age children and benefits of treatment from an endemic area in Zimbabwe

Abstract Background Schistosomiasis is known to affect the cognitive functions of children, however, but there is paucity of information on its impact on early childhood development in developing countries where the disease is endemic.This study aimed at determining the effects of schistosomiasis due to Schistosoma haematobium on early childhood de

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